быстрая доставка ~4 недели
Размер
- 100 μL
- 200 μL
- 50 μL
CYP24A1 Rabbit mAb (A22615)
- Описание
- Характеристики
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Overview
Product name CYP24A1 Rabbit mAb Catalog No. A22615 Host species Rabbit Purification method Affinity purification Isotype IgG CloneNo. ARC58733 Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1, 25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.Immunogen information
Immunogen Recombinant protein of human CYP24A1. Sequence Email for sequence Gene ID Swiss Prot Synonyms CP24; HCAI; CYP24; HCINF1; P450-CC24 Calculated MW 59kDa Observed MW Refer to figures Applications
Reactivity Human Tested applications IHC-P IF/ICC Recommended dilution - IHC-P 1:100 - 1:500
- IF/ICC 1:50 - 1:200
Storage buffer Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.Key application Immunohistochemistry Immunofluorescence Positive samples Cellular location Mitochondrion 
Immunohistochemistry analysis of paraffin-embedded human kidney using CYP24A1 Rabbit mAb (A22615) at dilution of 1:400 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Immunohistochemistry analysis of paraffin-embedded human liver using CYP24A1 Rabbit mAb (A22615) at dilution of 1:400 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Confocal imaging of A549 cells using CYP24A1 Rabbit mAb (A22615, dilution 1:200)(Red). The cells were counterstained with α-Tubulin Mouse mAb (AC012, dilution 1:400) (Green). DAPI was used for nuclear staining (blue). Objective: 100x.
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Key applications Immunohistochemistry, Immunofluorescence Host species Кролик Antibody type Primary Antibodies Reactivity Человек Immunogen Recombinant protein of human CYP24A1. Isotype IgG