быстрая доставка ~4 недели
Размер
- 100 μL
- 200 μL
- 50 μL
DSCR1 Rabbit mAb (A23086)
- Описание
- Характеристики
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Overview
Product name DSCR1 Rabbit mAb Catalog No. A23086 Host species Rabbit Purification method Affinity purification Isotype IgG CloneNo. ARC58928 Background
The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants.Immunogen information
Immunogen Recombinant protein of human DSCR1. Sequence Email for sequence Gene ID Swiss Prot Synonyms CSP1; DSC1; RCN1; DSCR1; MCIP1; ADAPT78 Calculated MW 28kDa Observed MW Refer to figures Applications
Reactivity Human, Mouse, Rat Tested applications IHC-P IF/ICC Recommended dilution - IHC-P 1:50 - 1:200
- IF/ICC 1:50 - 1:200
Storage buffer Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.Key application Immunohistochemistry Immunofluorescence Positive samples Cellular location cytoplasm, Nucleus 
Immunohistochemistry analysis of paraffin-embedded human kidney using DSCR1 Rabbit mAb (A23086) at dilution of 1:200 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Immunofluorescence analysis of U-2 OS cells using DSCR1 Rabbit mAb (A23086) at dilution of 1:50 (40x lens). Blue: DAPI for nuclear staining.
Immunofluorescence analysis of U-251MG cells using DSCR1 Rabbit mAb (A23086) at dilution of 1:50 (40x lens). Blue: DAPI for nuclear staining.
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Key applications Immunohistochemistry, Immunofluorescence Host species Кролик Antibody type Primary Antibodies Reactivity Человек, Мышь, Крыса Immunogen Recombinant protein of human DSCR1. Isotype IgG