быстрая доставка ~4 недели
Размер
- 100 μL
- 200 μL
- 50 μL
ITPR3 Rabbit mAb (A23202)
- Описание
- Характеристики
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Overview
Product name ITPR3 Rabbit mAb Catalog No. A23202 Host species Rabbit Purification method Affinity purification Isotype IgG CloneNo. ARC59549 Background
This gene encodes a receptor for inositol 1, 4, 5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1, 4, 5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth.Immunogen information
Immunogen Recombinant protein of human ITPR3. Sequence Email for sequence Gene ID Swiss Prot Synonyms IP3R; CMT1J; IP3R3 Calculated MW 304kDa Observed MW 300kDa Applications
Reactivity Human Tested applications WB Recommended dilution - WB 1:2000 - 1:6000
Storage buffer Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.Key application Western blotting Positive samples SW620, HEL(Negative control) Cellular location Endoplasmic reticulum membrane, Multi-pass membrane protein 
Western blot analysis of various lysates, using ITPR3 Rabbit mAb (A23202) at 1:5000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 60s. -
Key applications Western blotting Host species Кролик Antibody type Primary Antibodies Reactivity Человек Immunogen Recombinant protein of human ITPR3. Isotype IgG