быстрая доставка ~4 недели
Размер
- 100 μL
- 200 μL
- 50 μL
MUM1 Rabbit mAb (A23227)
- Описание
- Характеристики
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Overview
Product name MUM1 Rabbit mAb Catalog No. A23227 Host species Rabbit Purification method Affinity purification Isotype IgG CloneNo. ARC58086 Background
The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.Immunogen information
Immunogen Recombinant protein of human IRF4. Sequence Email for sequence Gene ID Swiss Prot Synonyms MUM1; LSIRF; SHEP8; NF-EM5 Calculated MW 52kDa Observed MW Refer to figures Applications
Reactivity Human Tested applications IHC-P Recommended dilution - IHC-P 1:50 - 1:200
Storage buffer Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.Key application Immunohistochemistry Positive samples Cellular location Nucleus 
Immunohistochemistry of paraffin-embedded Human anaplastic large cell lymphoma using IRF4 Rabbit mAb (A23227) at dilution of 1:400 (40x lens).Perform high pressure antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Immunohistochemistry of paraffin-embedded human appendix using IRF4 Rabbit mAb (A23227) at dilution of 1:400 (40x lens).Perform high pressure antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Immunohistochemistry of paraffin-embedded Human mantle cell lymphoma using IRF4 Rabbit mAb (A23227) at dilution of 1:400 (40x lens).Perform high pressure antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Immunohistochemistry of paraffin-embedded human tonsil using IRF4 Rabbit mAb (A23227) at dilution of 1:400 (40x lens).Perform high pressure antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
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Key applications Immunohistochemistry Host species Кролик Antibody type Primary Antibodies Reactivity Человек Immunogen Recombinant protein of human IRF4. KO Validated Validated Isotype IgG