быстрая доставка ~4 недели
Размер
- 100 μL
- 20 μL
- 200 μL
- 50 μL
Phospho-FLNA-S2152 Antibody kit (RK05766)
- Описание
- Характеристики
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Overview
Product name Phospho-FLNA-S2152 Antibody kit Catalog No. RK05766 Product Component
Product name Catalog No. Positive Applications Species Reactivity Phospho-Filamin A-S2152 Rabbit pAb AP0783 WB Human, Mouse, Rat Filamin A Rabbit pAb A7896 WB IHC-P Human, Mouse, Rat Background
The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.Immunogen information
Immunogen A synthetic peptide corresponding to a sequence within amino acids 2500 to the C-terminus of human Filamin A (NP_001104026.1).
A synthetic phosphorylated peptide around S2152 of human Filamin A (NP_001104026.1).Sequence KYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGLSKAYVGQKSSFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRVVVP
APSVAGene ID 2316 Swiss prot P21333 Synonyms FLN; FMD; MNS; OPD; ABPX; CSBS; CVD1; FGS2; FLN1; NHBP; OPD1; OPD2; XLVD; XMVD; FLN-A; ABP-280 Applications
Calculated MW 281kDa Observed MW 300kDa Storage buffer Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.Cellular location Cytoplasm,cell cortex,cytoskeleton 
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Antibody type Antibody Duos Reactivity Человек, Мышь, Крыса Immunogen A synthetic peptide corresponding to a sequence within amino acids 2500 to the C-terminus of human Filamin A (NP_001104026.1).A synthetic phosphorylated peptide around S2152 of human Filamin A (NP_001104026.1).