быстрая доставка ~4 недели
Размер
- 100 μL
- 20 μL
- 200 μL
- 50 μL
Phospho-NPM1-T199 Antibody kit (RK05773)
- Описание
- Характеристики
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Overview
Product name Phospho-NPM1-T199 Antibody kit Catalog No. RK05773 Product Component
Product name Catalog No. Positive Applications Species Reactivity Phospho-NPM1-T199 Rabbit pAb AP0836 WB Human NPM1 Rabbit pAb A17983 WB IHC-P IF/ICC Human, Mouse, Rat Background
The protein encoded by this gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia. Dozens of pseudogenes of this gene have been identified.Immunogen information
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 9-122 of human NPM1 (NP_002511.1).
A synthetic phosphorylated peptide around T199 of human NPM1 (NP_001032827.1).Sequence MSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIVEAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEED
RDTPAGene ID 4869 Swiss prot P06748 Synonyms B23; NPM Applications
Calculated MW 33kDa Observed MW 38kDa Storage buffer Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.Cellular location Cytoplasm,Nucleus,centrosome,cytoskeleton,microtubule organizing center,nucleolus,nucleoplasm 
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Antibody type Antibody Duos Reactivity Человек Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 9-122 of human NPM1 (NP_002511.1).A synthetic phosphorylated peptide around T199 of human NPM1 (NP_001032827.1).