быстрая доставка ~4 недели
Размер
- 100 μL
- 20 μL
- 200 μL
- 50 μL
Phospho-RELA-T435 Antibody kit (RK05777)
- Описание
- Характеристики
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Overview
Product name Phospho-RELA-T435 Antibody kit Catalog No. RK05777 Product Component
Product name Catalog No. Positive Applications Species Reactivity Phospho-NF-kB p65/RelA-T434 Rabbit pAb AP0838 WB Human, Mouse NF-kB p65/RelA Rabbit pAb A16271 WB IF/ICC Human, Mouse, Rat Background
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.Immunogen information
Immunogen A synthetic peptide corresponding to a sequence within amino acids 100-200 of human NF-kB p65/RelA (NP_068810.3).
A synthetic phosphorylated peptide around T435 of human RelA (NP_068810.3).Sequence YEAELCPDRCIHSFQNLGIQCVKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLSHPIFDNRAPNTAELKICRVN
EGTLSGene ID 5970 Swiss prot Q04206 Synonyms p65; CMCU; NFKB3; AIF3BL3 Applications
Calculated MW 60kDa Observed MW 58kDa Storage buffer Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.Cellular location Cytoplasm,Nucleus 
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Antibody type Antibody Duos Reactivity Человек, Мышь Immunogen A synthetic peptide corresponding to a sequence within amino acids 100-200 of human NF-kB p65/RelA (NP_068810.3).A synthetic phosphorylated peptide around T435 of human RelA (NP_068810.3).