Артикул
RK06002
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Phospho-SRC Family-Y416 Antibody kit (RK06002)
- Описание
- Характеристики
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Overview
Product name Phospho-SRC Family-Y416 Antibody kit Catalog No. RK06002 Product Component
Product name Catalog No. Positive Applications Species Reactivity Phospho-SRC Family-Y416 Rabbit pAb AP0480 WB Human, Mouse, Rat Src Rabbit pAb A18240 WB Human, Mouse, Rat Background
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.Immunogen information
Immunogen A synthetic peptide corresponding to a sequence within amino acids 450-536 of human Src (NP_005408.1).
A synthetic phosphorylated peptide around Y416 of human SRC Family (NP_005408.1).Sequence SFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
EDNEYGene ID 2534/3055/3932/4067/6714/7525 Swiss prot P06241/P08631/P06239/P07948/P12931/P07947 Synonyms ASV; SRC1; THC6; c-SRC; p60-Src; SRC Applications
Calculated MW 59kDa/60kDa Observed MW 60kDa Storage buffer Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.Cellular location Cell membrane,Cytoplasm,Mitochondrion inner membrane,Nucleus,cytoskeleton 
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Antibody type Antibody Duos Reactivity Человек, Мышь, Крыса Immunogen A synthetic peptide corresponding to a sequence within amino acids 450-536 of human Src (NP_005408.1).A synthetic phosphorylated peptide around Y416 of human SRC Family (NP_005408.1).