быстрая доставка ~4 недели
Размер
- 100 μg
- 1000 μg
Rabbit anti-Human IL-2 mAb (DET) (RM17590)
- Описание
- Характеристики
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Overview
Product name Rabbit anti-Human IL-2 mAb (DET) Catalog No. RM17590 Catagory Elisa Antibody Kit Application ELISA Description Interleukin-2 (IL-2) is an interleukin, a type of cytokine immune system signaling molecule, which is a leukocytotrophic hormone that is instrumental in the body’s natural response to microbial infection and in discriminating between foreign (non-self) and self. IL-2 mediates its effects by binding to IL-2 receptors, which are expressed by lymphocytes, the cells that are responsible for immunity. Mature human IL-2 shares 56% and 66% aa sequence identity with mouse and rat IL-2, respectively. Human and mouse IL-2 exhibit crossspecies activity. The receptor for IL-2 consists of three subunits that are present on the cell surface in varying preformed complexes. IL-2 is also necessary during T cell development in the thymus for the maturation of a unique subset of T cells that are termed regulatory T cells (T-regs). After exiting from the thymus, T-Regs function to prevent other T cells from recognizing and reacting against “self antigens“, which could result in “autoimmunity“. T-Regs do so by preventing the responding cells from producing IL-2. Thus, IL-2 is required to discriminate between self and non-self, another one of the unique characteristics of the immune system. Immunogen Recombinant IL-2 Protein Purirty Affinity purification Ig Type Rabbit IgG Endotoxin Level < 1.0 EU/μg of the protein by LAL method. Formulation Supplied as a 0.2um filtered solution in PBS with 0.1%Braveds MB-1, PH 7.4. CrossReactivity No cross-reactivity in ELISA assay with recombinant
hG-CSF、hGM-CSF、hIL-1β、hIL-1α、hIL-2R、hIL-3、hIL-4、hIL-6、hIL-8、hTGF-β 1、hTNF-α、mIL-1β、mIL-2、mIL-6、mIL-4、mIL-5 、mIL-2Storage This antibody can be stored at 2℃-8℃ for one monthwithout detectable loss of activity. Antibody products are stable for twelve months fromdate of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Application
Recommended
ConcentrationSample ELISA Capture 2-8ug/mL Rabbit anti-Human IL-2(CAP)(Cat. No.RM17589) ELISA Detection 0.15-0.6ug/mL Rabbit anti-Human IL-2(DET)(Cat. No.RM17590) Standard 0.78-50ng/mL Recombinant Human IL-2 Protein Rabbit anti-Human IL-2 mAb (DET) images
This standard curve is only for demonstration purposes. A standard curve should be generated for eachassay.No significant cross-reactivity or interference was observed.No significant cross-reactivity or interference was observed.
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Antibody type Matched antibody pairs Immunogen Recombinant IL-2 Protein
