быстрая доставка ~4 недели
Размер
- 100 μg
- 1000 μg
- 500 μg
Rabbit anti-Human IL-2R mAb (CAP) (RM17896)
- Описание
- Характеристики
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Overview
Product name Rabbit anti-Human IL-2R mAb (CAP) Catalog No. RM17896 Catagory Elisa Antibody Kit Application ELISA Description The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. Patients with severe Coronavirus Disease 2019 (COVID-19), the disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have significantly elevated levels of IL2R in their plasma. Similarly, serum IL-2R levels are found to be elevated in patients with different types of carcinomas. Certain IL2RA and IL2RB gene polymorphisms have been associated with lung cancer risk. Immunogen Recombinant Human IL-2R Purirty Affinity purification Ig Type Rabbit IgG Formulation Supplied as a 0.2um filtered solution in PBS with 0.05%ProClin 300, PH 7.8. CrossReactivity No cross-reactivity in ELISA assay withrecombinant
Human IFN-γ, Human IL-1α, Human IL-1β, Human IL-1ra, Human IL-2, Human IL-3, Human IL-4, Human IL-5, Human IL-6, Human IL-8, Human IL-9, Human IL-10, Human IL-11, Human IL-12, Human IL-13, Human M-CSF, Human TGF-β1, Human TNF-α, Mouse IL-1β, Mouse IL-4, Mouse IL-5, Mouse IL-6, Mouse IL-9, Mouse IL-10, Mouse IL-13, Mouse TNF-αStorage This antibody can be stored at 2℃-8℃ for one monthwithout detectable loss of activity. Antibody products are stable for twelve months fromdate of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Application
Recommended
ConcentrationSample ELISA Capture 1-4ug/mL Rabbit anti-Human IL-2R(CAP)(Cat. No.RM17896) ELISA Detection 0.01ug/mL-0.04ug/mL Rabbit anti-Human IL-2R(DET)(Cat. No.RM17897) Standard 31.25-2000pg/mL Recombinant Human IL-2R Protein Rabbit anti-Human IL-2R mAb (CAP) images
This standard curve is only for demonstration purposes. A standard curve should be generated for eachassay.No significant cross-reactivity or interference was observed.Placed at 37°C for 3 days, the stability of the standard curve all conformto CV <10%.
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Antibody type Matched antibody pairs Immunogen Recombinant Human IL-2R
