быстрая доставка ~4 недели
Размер
- 100 μg
- 1000 μg
- 500 μg
Rabbit anti-Mouse IL-17A mAb (CAP) (RM17904)
- Описание
- Характеристики
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Overview
Product name Rabbit anti-Mouse IL-17A mAb (CAP) Catalog No. RM17904 Catagory Elisa Antibody Kit Application ELISA Description Mouse IL-17A is an approximately 40 kDa, secreted, disulfide-linked heterodimeric glycoprotein comprised of two members of the IL-17 family of cytokines, IL-17A and IL-17F . Members of this family demonstrate a structural motif termed a cysteine knot that also characterizes a large superfamily of growth factors. Although most cysteine knot superfamily members use three intrachain disulfide bonds to create a knot, IL-17 family molecules generate the same structural form with only two disulfide links . Mouse IL-17A is synthesized as a 158 amino acid (aa) precursor that contains a 25 aa signal sequence and a 133 aa mature chain. The mature chain contains one potential site for N-linked glycosylation. Mouse IL-17F is synthesized as a 161 aa precursor with a 29 aa signal sequence and a 132 aa mature chain. Like IL-17A, the mature chain of IL-17F contains one potential site for N-linked glycosylation. IL-17A and IL-17F share 50% aa sequence homology and are syntenic, both located at the A4 region of mouse chromosome 1. Mouse IL-17A and IL-17F share 61% and 56% aa sequence identity with human IL-17A and IL-17F, respectively. Immunogen Recombinant Mouse IL-17A protein Purirty Affinity purification Ig Type Rabbit IgG Formulation Supplied as a 0.2um filtered solution in PBS with 0.05%ProClin 300, PH 7.8. CrossReactivity No cross-reactivity in ELISA assay withrecombinant
Mouse. GM-CSF , Mouse IL-1a, Mouse IL-1a, Mouse IL-2, Mouse IL-4, Mouse IL-5, Mouse IL-6, Mouse IL-9，Mouse IL-10，Mouse IL-12，Mouse Leptin，Mouse TNF-α，Mouse IL-1β，Human IL-17Storage This antibody can be stored at 2℃-8℃ for one monthwithout detectable loss of activity. Antibody products are stable for twelve months fromdate of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Application
Recommended
ConcentrationSample ELISA Capture 0.25-1ug/mL Rabbit anti-Mouse IL-17A (CAP)(Cat. No.RM17904) ELISA Detection 0.0025-0.01ug/mL Rabbit anti-Mouse IL-17A (DET)(Cat. No.RM17905) Standard 15.63-1000pg/mL Recombinant Mouse IL-17A Protein Rabbit anti-Mouse IL-17A mAb (CAP) images
This standard curve is only for demonstration purposes. A standard curve should be generated for eachassay.No significant cross-reactivity or interference was observed.Placed at 37°C for 3 days, the stability of the standard curve all conformto CV <10%.
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Antibody type Matched antibody pairs Immunogen Recombinant Mouse IL-17A protein
