быстрая доставка ~4 недели
Размер
- 100 μg
- 1000 μg
- 500 μg
Rabbit anti-Human Soluble Tyrosine-protein kinase receptor UFO(sAXL) mAb (DET) (RM17990)
- Описание
- Характеристики
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Overview
Product name Rabbit anti-Human Soluble Tyrosine-protein kinase receptor UFO(sAXL) mAb (DET) Catalog No. RM17990 Catagory Elisa Antibody Kit Application ELISA Description Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt), and Mer (human and mouse homologues of chicken c-Eyk) constitute a subfamily of the receptor tyrosine kinases . The extracellular domains of these proteins contain two Ig-like motifs and two fibronectin type III motifs. This characteristic topology is also found in neural cell adhesion molecules and in receptor tyrosine phosphatases. The human Axl cDNA encodes an 887 amino acid (aa) precursor that includes an 18 aa signal sequence, a 426 aa extracellular domain, a 21 aa transmembrane segment, and a 422 aa cytoplasmic domain. The extracellular domains of human and mouse Axl share 81% aa sequence identity. A short alternately spliced form of human Axl is distinguished by a 9 aa deletion in the extracellular juxtamembrane region. These receptors bind the vitamin K-dependent protein growth arrest specific gene 6 (Gas6) which is structurally related to the anticoagulation factor protein S. Binding of Gas6 induces receptor autophosphorylation and downstream signaling pathways that can lead to cell proliferation, migration, or the prevention of apoptosis . This family of tyrosine kinase receptors is involved in hematopoiesis, embryonic development, tumorigenesis, and regulation of testicular functions. Immunogen Recombinant Human sAXL Purirty Affinity purification Ig Type Rabbit IgG Formulation Supplied as a 0.2um filtered solution in PBS with 0.05%ProClin 300, PH 7.8. CrossReactivity / Storage This antibody can be stored at 2℃-8℃ for one monthwithout detectable loss of activity. Antibody products are stable for twelve months fromdate of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Application
Recommended
ConcentrationSample ELISA Capture 2-8ug/mL Rabbit anti-Human Soluble Tyrosine-protein kinase receptor UFO(sAXL) (CAP)(Cat. No.RM17989) ELISA Detection 0.0017-0.0067ug/mL Rabbit anti-Human Soluble Tyrosine-protein kinase receptor UFO(sAXL) (DET)(Cat. No.RM17990) Standard 0.16-10ng/mL Recombinant Human Soluble Tyrosine-protein kinase receptor UFO(sAXL) Protein Rabbit anti-Human Soluble Tyrosine-protein kinase receptor UFO(sAXL) mAb (DET) images
This standard curve is only for demonstration purposes. A standard curve should be generated for eachassay.
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Antibody type Matched antibody pairs Reactivity Человек Immunogen Recombinant Human sAXL
