быстрая доставка ~4 недели
Размер
- 100 μg
- 1000 μg
- 200 μg
- 500 μg
Rabbit anti-Human IL-10 mAb (DET) (RM17638)
- Описание
- Характеристики
-
Overview
Product name Rabbit anti-Human IL-10 mAb (DET) Catalog No. RM17638 Catagory Elisa Antibody Kit Application ELISA Description Interleukin-10 (IL-10) is also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine. IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. Mature human IL-10 shares 72% - 86% amino acid sequence identity with bovine, canine, equine, feline, mouse, ovine, porcine, and rat IL-10. Whereas human IL-10 is active on mouse cells, mouse IL-10 does not act on human cells. IL-10 is capable of inhibiting synthesis of pro-inflammatory cytokines such as IFN-γ, IL-2, IL-3, TNFα and GM-CSF made by cells such as macrophages and regulatory T-cells. It also displays a potent ability to suppress the antigen-presentation capacity of antigen presenting cells. However, it is also stimulatory towards certain T cells and mast cells and stimulates B cell maturation and antibody production. Knockout studies suggested the function of Interleukin-10 / IL-10 as an essential immunoregulator in the intestinal tract. Patients with Crohn’s disease react favorably towards treatment with bacteria producing recombinant interleukin-10, showing the importance of interleukin-10 for counteracting excessive immunity in the human body. Immunogen Recombinant IL-10 Protein Purirty Affinity purification Ig Type Rabbit IgG Formulation Supplied as a 0.2um filtered solution in PBS with 0.1%Braveds MB-1, PH 7.4. CrossReactivity No cross-reactivity in ELISA assay with recombinant
hIL-2、hIL-4、hIL-6Storage This antibody can be stored at 2℃-8℃ for one monthwithout detectable loss of activity. Antibody products are stable for twelve months fromdate of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Application
Recommended
ConcentrationSample ELISA Capture 1-4ug/mL Rabbit anti-Human IL-10(CAP)(Cat. No.RM17637) ELISA Detection 0.25-1ug/mL Rabbit anti-Human IL-10(DET)(Cat. No.RM17638) Standard 3.9-250pg/mL Recombinant Human IL-10 Protein Rabbit anti-Human IL-10 mAb (DET) images
This standard curve is only for demonstration purposes. A standard curve should be generated for eachassay.No significant cross-reactivity or interference was observed.No significant cross-reactivity or interference was observed.
-
Antibody type Matched antibody pairs Immunogen Recombinant IL-10 Protein
