быстрая доставка ~4 недели
Размер
- 100 μL
- 200 μL
- 50 μL
TrKC Rabbit mAb (A23002)
- Описание
- Характеристики
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Overview
Product name TrKC Rabbit mAb Catalog No. A23002 Host species Rabbit Purification method Affinity purification Isotype IgG CloneNo. ARC59398 Background
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene.Immunogen information
Immunogen A synthesized peptide derived from human TrKC. Sequence Email for sequence Gene ID Swiss Prot Synonyms TRKC; GP145-TrkC; gp145(trkC) Calculated MW 94kDa Observed MW 100kDa/145kDa Applications
Reactivity Human, Mouse, Rat Tested applications WB Recommended dilution - WB 1:500 - 1:1000
Storage buffer Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.Key application Western blotting Positive samples Mouse brain, Rat brain Cellular location axon, cytoplasm, glutamatergic synapse, plasma membrane, postsynaptic membrane 
Western blot analysis of Mouse brain, using TrKC antibody (A23002) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 180s.
Western blot analysis of Rat brain, using TrKC antibody (A23002) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit (RM00021).
Exposure time: 60s. -
Key applications Western blotting Host species Кролик Antibody type Primary Antibodies Reactivity Человек, Мышь, Крыса Immunogen A synthesized peptide derived from human TrKC. Isotype IgG