быстрая доставка ~4 недели
Размер
- 100 T
- 200 T
- 500 T
ABflo® 594 Rabbit anti-Human CLEC12A/CD371 mAb (A24581)
- Описание
- Характеристики
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Overview
Product name ABflo® 594 Rabbit anti-Human CLEC12A/CD371 mAb Catalog No. A24581 Host species Rabbit Purification method Affinity purification Isotype IgG CloneNo. ARC55557-ABflo594 Background
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13.Immunogen information
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 65-265 of human CLEC12A/CD371(NP_612210.4) Sequence HVTLKIEMKK MNKLQNISEE LQRNISLQLM SNMNISNKIR NLSTTLQTIA TKLCRELYSK EQEHKCKPCP RRWIWHKDSC YFLSDDVQTW QESKMACAAQ NASLLKINNK NALEFIKSQS RSYDYWLGLS PEEDSTRGMR VDNIINSSAW VIRNAPDLNN MYCGYINRLY VQYYHCTYKK RMICEKMANP VQLGSTYFRE A Gene ID Swiss Prot Synonyms CLEC12A; CD371; CLL-1; CLL1; DCAL-2; MICL; C-type lectin domain family 12 member A Calculated MW 8kDa/24kDa/27kDa/30kDa/32kDa Observed MW Applications
Reactivity Human Tested applications FC Recommended dilution - FC 5 μl per 10^6 cells in 100 μl volume
Storage buffer Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.03% proclin300, 0.2% BSA, 50% glycerol, pH7.3.Key application Flow Cytometry Positive samples Cellular location Cell membrane, Single-pass type II membrane protein 
Flow cytometry:1X10^6 K-562 cells (negative control, left) and U-937 cells (right) were surface-stained with ABflo® 594 Rabbit anti-Human CLEC12A/CD371 mAb(A24581, 5 μl/Test, orange line) or ABflo® 594 Rabbit IgG isotype control (A23821, 5 μl/Test, blue line). Non-fluorescently stained cells were used as blank control (red line).
Flow cytometry:1X10^6 U-937 cells were surface-stained with ABflo® 594 Rabbit IgG isotype control (A23821, 5 μl/Test, left) or ABflo® 594 Rabbit anti-Human CLEC12A/CD371 mAb(A24581, 5 μl/Test, right).
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Key applications Flow Cytometry Host species Кролик Antibody type Primary Antibodies Reactivity Человек Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 65-265 of human CLEC12A/CD371(NP_612210.4) Isotype IgG