быстрая доставка ~4 недели
Размер
- 100 μL
- 200 μL
- 50 μL
TREX1 Rabbit mAb (A3819)
- Описание
- Характеристики
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Overview
Product name TREX1 Rabbit mAb Catalog No. A3819 Host species Rabbit Purification method Affinity purification Isotype IgG CloneNo. ARC0841 Background
This gene encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants.Immunogen information
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 150-314 of human TREX1 (Q9NSU2). Sequence AFCVDSITALKALERASSPSEHGPRKSYSLGSIYTRLYGQSPPDSHTAEGDVLALLSICQWRPQALLRWVDAHARPFGTIRPMYGVTASARTKPRPSAVTTTAHLATTRNTSPSLGESRGTKDLPPVKDPGALSREGLLAPLGLLAILTLAVATLYGLSLATPGE Gene ID Swiss Prot Synonyms CRV; AGS1; DRN3; HERNS; RVCLS Calculated MW 33kDa Observed MW 33kDa Applications
Reactivity Human Tested applications WB Recommended dilution - WB 1:500 - 1:2000
Storage buffer Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.Key application Western blotting Positive samples HeLa, HT-29, Jurkat Cellular location Cytoplasm, Endoplasmic reticulum membrane, Nucleus, Peripheral membrane protein, Cytosol 
Western blot analysis of extracts of various cell lines, using TREX1 Rabbit mAb (A3819) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 10s. -
Key applications Western blotting Host species Кролик Antibody type Primary Antibodies Reactivity Человек Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 150-314 of human TREX1 (Q9NSU2). Isotype IgG