быстрая доставка ~4 недели
Размер
- 100 μL
- 20 μL
- 200 μL
- 50 μL
2'-O-Methylguanosine(Gm) Rabbit pAb (A20697)
- Описание
- Характеристики
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Overview
Product name 2'-O-Methylguanosine(Gm) Rabbit pAb Catalog No. A20697 Host species Rabbit Purification method Affinity purification Isotype IgG Background
RNA methylation plays a significant regulatory role in various of physiological activities and it has gradually become a hotspot of epigenetics in the past decade. 2'-O-methyladenosine (Am), 2'-O-methylguanosine (Gm), 2'-O-methylcytidine (Cm), 2'-O-methyluridine (Um), N 6-methyladenosine (m6A), N 1-methylguanosine (m1G), 5-methylcytidine (m5C), and 5-methyluridine (m5U) are representative 2'-O-methylation and base-methylation modified epigenetic marks of RNA. 2'-O-methyltransferase is a modified nucleoside that is produced in tRNAs by the action of tRNA guanosine-2'-O-methyltransferase, using S-adenosyl-L-methionine as a substrate. Through its interaction with other modified nucleosides, 2'-O-methylguanosine is thought to stabilize the structure of the tRNA.Immunogen information
Immunogen Gm Sequence Gm conjugated to KLH Gene ID Swiss Prot Synonyms Calculated MW Observed MW Refer to figures Applications
Reactivity Species independent Tested applications DB Recommended dilution - DB 1:500 - 1:2000
Storage buffer Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.Key application Positive samples Cellular location 
The 2'-O-methylguanosine(Gm) Rabbit pAb(A20697) are tested in Dot Blot against 2'-O-methylguanosine(Gm) and unmodified guanosine. Gm-3：5'Biotin-GCATAATGACTACT(Gm)3' Gm-4：5'Biotin-GCATAATGACTACTG3'
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Host species Кролик Antibody type Primary Antibodies Reactivity Независимый от вида Immunogen Gm Isotype IgG