- Описание
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Product Information
Description
ALDH1L1 mouse monoclonal antibody
Protein full name
Cytosolic 10-formyltetrahydrofolate dehydrogenase
Synonyms
10-FTHFDH, FDH, Aldehyde dehydrogenase family 1 member L1, Aldh1l1, Fthfd, ALDH1L1
Immunogen
Recombinant protein corresponding to Mouse ALDH1L1
Isotype
IgG
Purity
Affinity purification
Predicted MW.
99 kDa
Observed MW.
99 kDa
Uniprot ID
Q8R0Y6, P28037
Applications
Applications
Species
Dilution
Positive Tissue
WB
Mouse, Rat
1: 500-1: 1000
brain, kidney, liver, pancreas
Background
Aldehyde dehydrogenase 1 family member L1 (ALDH1L1), belongs to the aldehyde dehydrogenase family of proteins and is responsible for formate oxidation in vivo. Loss of ALDH1L1 is associated with decreased apoptosis, increased cell motility, and cancer progression. ALDH1L1 catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.
Images

Western blot analysis of ALDH1L1 (GB12665) at dilution of 1: 1000
Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).







