- Описание
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Product Information
Description
14-3-3 alpha + beta mouse monoclonal antibody
Protein full name
14-3-3 protein beta/alpha
Synonyms
YWHAB, GW128, HEL-S-1, KCIP-1, YWHAA, HS1, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse 14-3-3 alpha + beta
Isotype
IgG
Purity
Affinity purification
Subcellular location
Cytoplasm
Uniprot ID
Q9CQV8, P35213,P31947
Applications
Applications
Species
Dilution
Positive Sample
IHC/IF
Human, Mouse, Rat
1:500-1:1000
colon, esophagus cancer, fetal rat, intestine cancer, skin
Background
This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery.
Images

Immunohistochemistry of paraffin embedded human colon using 14-3-3 (GB12592) at dilution of 1: 1000 (380x lens) 
Immunohistochemistry of paraffin embedded human esophagus cancer using 14-3-3 (GB12592) at dilution of 1: 1000 (380x lens) 
Immunofluorescence of paraffin embedded human intestine cancer using 14-3-3α (GB12592) at dilution of 1: 500 (400x lens) 
Immunofluorescence of paraffin embedded mouse fetal rat using 14-3-3α (GB12592) at dilution of 1: 500 (400x lens) 
Immunofluorescence of paraffin embedded rat colon using 14-3-3α (GB12592) at dilution of 1: 500 (400x lens) 
Immunofluorescence of paraffin embedded rat skin using 14-3-3α (GB12592) at dilution of 1: 500 (400x lens) Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).










