Product Information
| Description | Hexokinase II mouse monoclonal |
| Protein full name | Hexokinase-2 |
| Synonyms | Hexokinase type II, HK II,Hk2, Muscle form hexokinase, muscle |
| Immunogen | Recombinant protein corresponding to Mouse Hexokinase II |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 103 kDa |
| Observed MW. | 103 kDa |
| Uniprot ID | P52789,O08528,P27881 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat | 1: 500-1: 1000 | heart, lung, muscle |
Background
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
Images
| Western blot analysis of Hexokinase II (GB121063) at dilution of 1: 1000 Lane 1: A549 cell lysate Lane 2: MCF7 cell lysate Lane 3: C2C12 cell lysate Lane 4: Mouse heart tissue lysate Lane 5: Mouse lung tissue lysate Lane 6: Mouse muscle tissue lysate Lane 7: Rat heart tissue lysate Lane 8: Rat muscle tissue lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
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