Артикул
GB113664
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Anti -alpha Sarcoglycan Rabbit pAb
- Описание
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Product Information
Description
alpha Sarcoglycanrabbit polyclonal
Protein full name
Alpha-sarcoglycan
Synonyms
50-DAG, 50DAG, A2, adhalin, ADL, Alpha SG, DAG2, DMDA2, Dystroglycan 2, LGMD2D, SCARMD1, SGCA
Immunogen
KLH conjugated Synthetic peptide
corresponding to Mouse alpha Sarcoglycan
Isotype
IgG
Purity
Affinity purification
Subcellular location
Predicted MW.
43 kDa
Observed MW.
55kDa
Uniprot ID
Applications
Applications
Species
Dilution
Positive Tissue
WB
Human, Mouse, Rat
1:300-1:600
heart, skeletal muscle
IHC
Mouse
1:300-1:600
skeletal muscle
Background
Alpha-sarcoglycan is a member of the sarcoglycan-sarcospan complex (SG-SSPN), which is constituted by α/ɛ-, β-, γ-, and δ-SGs as well as SSPN. Alpha-sarcoglycan gene expression is exclusive of striated muscle and is finely regulated during myogenic differentiation, where the amount of alpha-sarcoglycan transcript is selectively increased after differentiation to myotubes (MTs). Alpha sarcoglycan's disruption causes limb-girdle muscular dystrophy.
Images
Western blot analysis of SGCA (GB113664) at dilution of 1: 600 
Immunohistochemistry analysis of paraffin-embedded mouse skeletal muscle using SGCA (GB113664) at dilution of 1: 600 Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.