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Product Information
| Description | Acetylcholinesterase rabbit polyclonal |
| Protein full name | Acetylcholinesterase |
Synonyms | AchE, acetylhydrolase, acetylcholinesteraseACEE, ARN-YT, acetylcholinesterase, AChE |
| Immunogen | KLH conjugated Synthetic peptidecorresponding to Mouse AchE |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location | Cell membrane, Secreted, Synapse |
| Uniprot ID |
Applications
| Applications | IHC, IF | ||
| Species | Mouse, Rat | ||
| Dilution | 1:500-1:2000 | ||
| Positive tissue | brain |
Background
Acetylcholinesterase, also known as AchE or acetylhydrolase, is the primary cholinesterase in the body. It is an enzyme that catalyzes the breakdown of acetylcholine and of some other choline esters that function as neurotransmitters. AchE is found at mainly neuromuscular junctions and in chemical synapses of the cholinergic type, where its activity serves to terminate synaptic transmission. It belongs to carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides.
Images
| Immunohistochemistry analysis of paraffin-embedded rat brain using AchE(GB11038-1) at dilution of 1:800 |
| Immunohistochemistry analysis of paraffin-embedded mouse brain using AchE(GB11038-1) at dilution of 1:800 |
