- Описание
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Product Information
Description
Alpha-synuclein rabbit polyclonal antibody
Protein full name
Alpha-synuclein
Synonyms
SNCA, NACP, PARK1, PARK4, PD1, synuclein alpha, α-synuclein
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse α-synuclein
Isotype
IgG
Purity
Affinity purification
Subcellular location
Predicted MW.
14 kDa
Observed MW.
19 kDa
Uniprot ID
P37840, O55042, P37377
Applications
Applications
Species
Dilution
Positive Sample
WB
Human, Mouse, Rat
1: 300-1: 600
brain, cerebral cortex
IHC/IF
Mouse,Rat
1:1000-1:2000
brain, cerebellum
Background
Alpha-synuclein is a protein that, in humans, is encoded by the SNCA gene. It is abundant in the brain while smaller amounts are found in the heart, muscles, and other tissues. In the brain, alpha-synuclein is found mainly at the tips of nerve cells (neurons) in specialized structures called presynaptic terminals. Within these structures, alpha-synuclein interacts with phospholipids and proteins. Presynaptic terminals release chemical messengers, called neurotransmitters, from compartments known as synaptic vesicles. The release of neurotransmitters relays signals between neurons and is critical for normal brain function.
Images

Western blot analysis of SNCA (GB11404) at dilution of 1: 300

Immunohistochemistry analysis of paraffin-embedded mouse brain using
α-synuclein GB11404 at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded rat brain using
α-synuclein GB11404 at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded mouse cerebellum using
α-synuclein GB11404 at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded rat cerebellum using
α-synuclein GB11404 at dilution of 1: 1000
Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).












