Product Information
| Description | GFAP rabbit polyclonal |
| Protein full name | Glial fibrillary acidic protein |
Synonyms | GFAP, ALXDRD, glial fibrillary acidic protein |
| Immunogen | KLH conjugated Synthetic peptidecorresponding to Mouse GFAP |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 49KDa |
Observed MW. | 49KDa |
Subcellular location | Cytoplasm |
| Uniprot ID | P14136,P03995,P47819 |
Applications
| Applications | WB | IHC | IF |
| Species | Human, Rat, Mouse | Rat, Mouse | Rat, Mouse |
| Dilution | 1:2000 | 1:1000-1:2000 | 1:500-1:1000 |
| Positive tissue | Brain, U251, C6 | brain | brain |
Background
Glial fibrillary acidic protein is anintermediate filament(IF) protein that is expressed by numerous cell types of thecentral nervous system(CNS) includingastrocytesandependymal cells.GFAP has also been found to be expressed inglomeruliand peritubular fibroblasts taken from rat kidneysLeydig cellsof the testis in both hamstersand humans,humankeratinocytes,humanosteocytesandchondrocytesand stellate cells of thepancreasandliverin rats.It is closely related to its non-epithelial family members,vimentin,desmin, andperipherin, which are all involved in the structure and function of the cell’scytoskeleton.
Images
| Western blot analysis of GFAP(GB11096) at dilution of 1:2000. Line 1: U251 cell lysate Line 2: C6 cell lysate Line 3: Mouse brain tissue lysate Line 4: Rat brain tissue lysate |
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| Immunohistochemistry analysis of paraffin-embedded mouse brain using GFAP (GB11096) at dilution of 1:1000 |
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| Immunohistochemistry analysis of paraffin-embedded rat brain using GFAP (GB11096) at dilution of 1:1000 |
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| Immunofluorescence analysis of paraffin-embedded mouse brain using GFAP (GB11096) at dilution of 1:500 |
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| Immunofluorescence analysis of paraffin-embedded rat brain using GFAP (GB11096) at dilution of 1:500 |
