Артикул
GB11664
быстрая доставка ~4 недели
Наши менеджеры обязательно свяжутся с вами и уточнят условия заказа
Anti -ACTH Rabbit pAb
- Описание
-
Product Information
Description
ACTH rabbit polyclonalantibody
Protein full name
Pro-opiomelanocortin
Synonyms
POMC, ACTH, CLIP, LPH, MSH, NPP, POC, proopiomelanocortin, OBAIRH, Pomc
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse ACTH
Isotype
IgG
Purity
Affinity purification
Predicted MW.
27 kDa
Observed MW.
30 kDa
Uniprot ID
Applications
Applications
Species
Dilution
Positive Tissue
WB
Mouse, Rat
1:250-1:500
hypophysis, brain, cerebral cortex
Background
Pro-opiomelanocortin (POMC) is a precursor polypeptide with 266 amino acid residues. POMC is synthesized in the pituitary from the 285-amino-acid-long polypeptide precursor pre-pro-opiomelanocortin (pre-POMC), by the removal of a 44-amino-acid-long signal peptide sequence during translation. POMC is cleaved to give rise to multiple peptide hormones(α-MSH, ACTH, β-Endorphin and [Met]enkephalin). Adrenocorticotropic hormone (ACTH, also adrenocorticotropin, corticotropin) is a polypeptide tropic hormone produced by and secreted by the anterior pituitary gland. It is also used as a medication and diagnostic agent.. ACTH is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress. Its principal effects are increased production and release of cortisol by the cortex of the adrenal gland. ACTH is also related to the circadian rhythm in many organisms.
Images
Western blot analysis of ACTH (GB11664) at dilution of 1: 250
Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.