- Описание
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Product Information
Description
14-3-3 gamma rabbit polyclonal antibody
Protein full name
14-3-3 protein gamma
Synonyms
YWHAG, 14-3-3gamma, PPP1R170, tyrosine 3-monooxygenase, EIEE56, tryptophan 5-monooxygenase activation protein gamma,
Immunogen
Recombinant protein corresponding to Mouse 14-3-3 gamma
Isotype
IgG
Purity
Affinity purification
Predicted MW.
28 kDa
Observed MW.
32 kDa
Uniprot ID
P61981, P61982, P61983
Applications
Applications
Species
Dilution
Positive Sample
WB
Human, Mouse, Rat
1: 1000-1: 2000
brain, testis, lung
Background
14-3-3 protein gamma is a protein that is encoded by the YWHAG gene. This gene product belongs to the 14-3-3 protein family which mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms comprise this family of signaling intermediates, denoted 14-3-3 b, g, e, z, h, q and s. 14-3-3 proteins form dimers that present two binding sites for ligand proteins, thereby bringing together two proteins that may not otherwise associate. These ligands largely share a 14-3-3 consensus binding motif and exhibit serine/threonine phosphorylation.
Images

Western blot analysis of 14-3-3γ (GB11578) at dilution of 1: 1000
Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles
Storage Buffer PBS with 0.02%sodium azide, 100 μg/ml BSA and 50% glycerol.
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).







