Артикул
GB113776
быстрая доставка ~4 недели
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Anti -alpha Actinin 4 Rabbit pAb
- Описание
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Product Information
Description
alpha Actinin 4 rabbit polyclonal
Protein full name
Alpha-actinin-4
Synonyms
ACTININ 4, actinin, alpha 4, ACTN4, F actin cross linking protein, FSGS, FSGS1, Non muscle alpha actinin 4
Immunogen
KLH conjugated Synthetic peptide
corresponding to Mouse alpha Actinin 4
Isotype
IgG
Purity
Affinity purification
Predicted MW.
105 kDa
Observed MW.
105kDa
Uniprot ID
Applications
Applications
Species
Dilution
Positive Tissue
WB
Mouse
1:300-1:1000
liver, small intestine
Background
ACTN4 (alpha actinin 4) is a ubiquitous actin-binding protein that cross-links actin filaments into bundles to form filopodia, and has a crucial role in cytoskeletal organization. ACTN4 is colocalized with actin stress fibers and is dispersed in the cytoplasm and in the nucleus. Increased levels of ACTN4 have been associated with cancer metastasis, indicating its implication in cancer cell migration and metastasis. Defects in ACTN4 cause glomerular disease. This antibody recognizes 100-105 kDa of endogenous ACTN4 protein in various lysates.
Images
Western blot analysis of ACTN4 (GB113776)
at dilution of 1: 1000
Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.