- Описание
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Product Information
Description
AF10rabbit polyclonal
Protein full name
Protein AF-10
Synonyms
ALL1-fused gene from chromosome 10 protein,MLLT10, AF10, Type I AF10 protein
Immunogen
KLH conjugated Synthetic peptide
corresponding to Human AF10
Isotype
IgG
Purity
Affinity purification
Subcellular location
Nucleus
Uniprot ID
Applications
Applications
Species
Dilution
Positive Tissue
IHC
Mouse, Rat
1:600-1:1200
testis
Background
Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA. In cells, binding to unmodified histone H3 regulates DOT1L functions including histone H3 'Lys-79' dimethylation (H3K79me2) and gene activation.
Images

Immunohistochemistry analysis of paraffin-embedded mouse testis using
AF10 (GB112809) at dilution of 1: 1200

Immunohistochemistry analysis of paraffin-embedded rat testis using
AF10 (GB112809) at dilution of 1: 1200
Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).









