Артикул
GB112407
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Anti -ABHD6 Rabbit pAb
- Описание
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Product Information
Description
ABHD6 rabbit polyclonal antibody
Protein full name
Monoacylglycerol lipase ABHD6
Synonyms
2-arachidonoylglycerol hydrolase, Abhydrolase domain-containing protein 6, Abhd6
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse ABHD6
Isotype
IgG
Purity
Affinity purification
Predicted MW.
38 kDa
Observed MW.
38 kDa
Uniprot ID
Q8R2Y0, Q5XI64
Applications
Applications
Species
Dilution
Positive Sample
WB
Mouse, Rat
1: 500-1: 1000
liver, brown fat, brain, small intestine
Background
Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2AG, an inhibitor of the sperm calcium channel CatSper, leading to calcium influx via CatSper and sperm activation . Involved in acrosomal reaction (Probable). May also play a role in smooth muscle cells migration .
Images
Western blot analysis of Abhd6 (GB112407) at dilution of 1: 500
Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.