- Описание
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Product Information
Description
ZO1 tight junction protein rabbit polyclonal antibody
Protein full name
Tight junction protein ZO-1
Synonyms
TJP1, ZO-1, Tight junction protein 1
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse ZO-1
Isotype
IgG
Purity
Affinity purification
Subcellular location
Cell membrane, Cell junction
Uniprot ID
Q07157, P39447
Applications
Applications
Species
Dilution
Positive Sample
IHC/IF
Human, Mouse, Rat
1: 200-1: 1200
brain, colon cancer, duodenum, jejunum, small intestine
Background
The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.
Images

Immunohistochemistry of paraffin embedded human brain using ZO-1 (GB111981) at dilution of 1:1200 (100x lens)

Immunohistochemistry of paraffin embedded mouse small intestine using ZO-1 (GB111981) at dilution of 1:1200 (200x lens)

Immunohistochemistry of paraffin embedded rat brain using ZO-1 (GB111981) at dilution of 1:1200 (100x lens)

Immunohistochemistry of paraffin embedded rat jejunum using ZO-1 (GB111981) at dilution of 1:1200 (100x lens) 
Immunohistochemistry of paraffin embedded rat small intestine using ZO-1 (GB111981) at dilution of 1:1200 (200x lens) 
Immunofluorescence of paraffin embedded human colon cancer using ZO-1 (GB111981) at dilution of 1:800 (40x lens)

Immunofluorescence of paraffin embedded mouse duodenum using ZO-1 (GB111981) at dilution of 1:800 (100x lens) 
Immunofluorescence of paraffin embedded mouse small intestine using ZO-1 (GB111981) at dilution of 1:800 (100x lens) 
Immunofluorescence of paraffin embedded rat small intestine using ZO-1 (GB111981) at dilution of 1:800 (100x lens) Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).













