Артикул
GB111694
быстрая доставка ~4 недели
Поликлональные антитела кролика к GSK3 beta (Anti-GSK3 beta Rabbit pAb)
- Описание
-
Product Information
Description
GSK3 beta rabbit polyclonal
Protein full name
Glycogen synthase kinase-3 beta
Synonyms
GSK3B, Gsk3b, 7330414F15Rik, 8430431H08Rik, C86142, GSK-3, GSK-3beta, GSK3, glycogen synthase kinase 3 beta
Immunogen
Recombinant protein corresponding to Mouse GSK3 beta
Isotype
IgG
Purity
Affinity purification
Subcellular location
Predicted MW.
47 kDa
Observed MW.
47 kDa
Uniprot ID
Applications
Applications
Species
Dilution
Positive Tissue
WB
Human, Mouse, Rat
1: 500-1: 1000
brain, heart
IHC Human, Mouse, Rat
1: 500-1: 1000
ovary, ovarian cancer, gastric cancer, breast cancer, brain, testis, kidney
Background
Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase .GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation.In skeletal muscle, it contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. Researches showed that the crystal structure of human GSK3B, expressed in insect cells, at 2.8-angstrom resolution .This antibody recognize the C-terminal of GSK3B.
Images
Western blot analysis of GSK3 beta (GB111694)
at dilution of 1: 1000
Lane 1: HeLa cell lysate
Lane 2: A431 cell lysate
Lane 3: NIH3T3 cell lysate
Lane 4: Mouse brain tissue lysate
Lane 5: Mouse heart tissue lysate
Lane 6: Rat brain tissue lysate
Immunohistochemistry analysis of paraffin-embedded human ovary using
GSK3 beta (GB111694) at dilution of 1: 1000
Immunohistochemistry analysis of paraffin-embedded human ovarian cancer using
GSK3 beta (GB111694) at dilution of 1: 1000
Immunohistochemistry analysis of paraffin-embedded human gastric cancer using GSK3 beta (GB111694) at dilution of 1: 1000 Immunohistochemistry analysis of paraffin-embedded human breast cancer using GSK3 beta (GB111694) at dilution of 1: 1000 Immunohistochemistry analysis of paraffin-embedded rat brain using
GSK3 beta (GB111694) at dilution of 1: 1000
Immunohistochemistry analysis of paraffin-embedded mouse brain using
GSK3 beta (GB111694) at dilution of 1: 1000
Immunohistochemistry analysis of paraffin-embedded mouse testis using
GSK3 beta (GB111694) at dilution of 1: 100
Immunohistochemistry analysis of paraffin-embedded mouse kidney using
GSK3 beta (GB111694) at dilution of 1: 1000
Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.