Артикул
GB111060
быстрая доставка ~4 недели
Наши менеджеры обязательно свяжутся с вами и уточнят условия заказа
Anti -5HT1A Receptor Rabbit pAb
- Описание
-
Product Information
Description
5HT1A Receptor rabbit polyclonal antibody
Protein full name
5-hydroxytryptamine receptor 1A
Synonyms
5-HT-1A, G-21, Serotonin receptor 1A, HTR1A, ADRB2RL1,ADRBRL1
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse 5HT1A Receptor
Isotype
IgG
Purity
Affinity purification
Predicted MW.
46 kDa
Observed MW.
46 kDa
Uniprot ID
P08908
Applications
Applications
Species
Dilution
Positive Tissue
WB
Human
1: 500-1: 1000
Jurkat, CACO-2, Raji, HepG2, HCT116
Background
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5- hydroxytryptamine release and in the regulation of dopamine and 5- hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.
Images
Western blot analysis of 5-HT1A (GB111060) at dilution of 1: 500
Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.