быстрая доставка ~4 недели
Размер
- 10 μg
- 20 μg
- 50 μg
Active Recombinant Human S100-A12 Protein (RP00009LQ)
- Описание
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Overview
Product name Active Recombinant Human S100-A12 Protein Catalog No. RP00009LQ Description Active Recombinant Human S100-A12 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Glu92) of human S100A12 (Accession #NP_005612.1) fused with a 6×His tag at the C-terminus. Bio-Activity Measured by its binding ability in a functional ELISA. Immobilized Human S100A12 at 2 μg/mL (100 μL/well) can bind recombinant Human AGER/RAGE with a linear range of 0.1-27.25 ng/mL. Purity > 97% by SDS-PAGE. Endotoxin < 0.1 EU/μg of the protein by LAL method. Formulation Supplied in PBS, 25% glycerol, pH 7.4Contact us for customized product form or formulation. Species Human Background
The protein is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 proteins include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity.Product information
Synonym CAAF1; CAGC; CGRP; ENRAGE; MRP-6; MRP6; p6 Expression Host E. coli Tag C-His Swiss-Prot Gene ID Usage guide
Storage This product is stable at ≤ -70° C for up to 1 year from the date of receipt.
For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature.* For research use only. Not for therapeutic or diagnostic purposes.
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