быстрая доставка ~4 недели
Размер
- 10 μg
- 100 μg
- 20 μg
- 50 μg
Рекомбинантный человеческий белок миелин-олигодендроцит (MOG) (Recombinant Human Myelin-oligodendrocyte glycoprotein/MOG Protein)
- Описание
-
Overview
Product name Recombinant Human Myelin-oligodendrocyte glycoprotein/MOG Protein Catalog No. RP01361 Description Recombinant Human Myelin-oligodendrocyte glycoprotein/MOG Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly30-Gly154) of human MOG (Accession #NP_996532.2) fused with a 6×His tag at the C-terminus. Bio-Activity Measured by its binding ability in a functional ELISA. Immobilized Human MOG at 1 μg/mL (100 μL/well) can bind Myelin oligodendrocyte glycoprotein Rabbit mAb with a linear range of 0.98-2.5 ng/mL Purity > 95% by SDS-PAGE. Endotoxin <0.1EU/ug Formulation Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Species Human Background
Myelin oligodendrocyte glycoprotein (MOG) is a transmembrane protein belonging to the immunoglobulin superfamily and contains an Ig-like domain followed by two potential membrane-spanning regions. MOG is expressed only in the CNS with very low content (approximately 0.1% total proteins) in the oligodendrogliocyte membrane. Three possible functions for MOG were suggested: (a) a cellular adhesive molecule, (b) a regulator of oligodendrocyte microtubule stability, and (c) a mediator of interactions between myelin and the immune system, in particular, the complement cascade. A direct interaction might exist between the membrane-associated regions of MOG and the myelin-specific glycolipid galactocerebroside (Gal-C), and such an interaction may have important consequences regarding the membrane topology and function of both molecules. It is considered that MOG is an autoantigen capable to produce demyelinating multiple sclerosis-like diseases in experimental animals.Product information
Synonym MOG; BTN6; BTNL11; MOGIG2; NRCLP7 Expression Host HEK293 cells Tag C-His Swiss-Prot Gene ID Usage guide
Storage Store the lyophilized protein at -20°C to -80°C for long term.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. * For research use only. Not for therapeutic or diagnostic purposes.
Product Protocols