быстрая доставка ~4 недели
Размер
- 10 μg
- 100 μg
Recombinant SARS-CoV Spike S1 Protein (RP01302)
- Описание
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Overview
Product name Recombinant SARS-CoV Spike S1 Protein Catalog No. RP01302 Description Recombinant Recombinant SARS-CoV Spike S1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ser14-Arg667) of sars-cov Spike S1 (Accession #NP_828851.1) fused with a mFc tag at the C-terminus. Purity > 90% by SDS-PAGE. Endotoxin < 1.0 EU/μg of the protein by LAL method. Formulation Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Species SARS-CoV Background
The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. The main functions for the Spike protein are summarized as: Mediate receptor binding and membrane fusion; Defines the range of the hosts and specificity of the virus; Main component to bind with the neutralizing antibody; Key target for vaccine design; Can be transmitted between different hosts through gene recombination or mutation of the receptor binding domain (RBD), leading to a higher mortality rate.Product information
Synonym coronavirus s1 Protein; SARS; ncov s1 Protein; SARS; S1 Protein; SARS Expression Host HEK293 cells Tag C-mFc Swiss-Prot Gene ID Usage guide
Storage Store the lyophilized protein at -20°C to -80°C for long term.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. * For research use only. Not for therapeutic or diagnostic purposes.
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