быстрая доставка ~4 недели
Размер
- 100 μg
- 200 μg
- 50 μg
- 500 μg
Active Recombinant Human CEACAM-1/CD66a Protein (RP00294)
- Описание
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Overview
Product name Active Recombinant Human CEACAM-1/CD66a Protein Catalog No. RP00294 Description Active Recombinant Human CEACAM-1/CD66a Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln35-Gly428) of human CEACAM1 (Accession #NP_001703.2) fused with a 6×His tag at the C-terminus. Bio-Activity Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human CEACAM1 at 5 μg/mL (100 μL/well) can bind Recombinant Human CEACAM8 with a linear range of 0.5-3 μg/mL. Purity > 97% by SDS-PAGE. Endotoxin Please contact us for more information. Formulation Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation. Species Human Background
The secreted recombinant human CEACAM1 comprises 405amino acids with a molecular weight of 45 kDa. The apparent molecular mass of recombinant human CEACAM1 is about 65-85 kDa in SDS-PAGE under reducing conditions due to glycosylation.Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is also known as Biliary glycoprotein 1 (BGP1), CD66a belonging to the immunoglobulin superfamily or CEA family. CEACAM1 /CD66a contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CEACAM1 is a surface glycoprotein expressed on various blood cells, epithelial cells, and vascular cells and was described as an adhesion molecule mediating cell adhesion via both homophilic and heterophilic manners, and was detected on leukocytes, epithelia, and endothelia.The carcinoembryonic-antigen-related cell-adhesion molecule (CEACAM) family of proteins has been implicated in various intercellular-adhesion and intracellular-signalling-mediated effects that govern the growth and differentiation of normal and cancerous cells. Studies have revealed that CEACAM1 performs actions in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses.Product information
Synonym BGP; BGP1; BGPI; CD66a; CEACAM1 Expression Host HEK293 cells Tag C-His Swiss-Prot Gene ID Usage guide
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. * For research use only. Not for therapeutic or diagnostic purposes.
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