быстрая доставка ~4 недели
Размер
- 100 μg
- 20 μg
- 200 μg
- 50 μg
- 500 μg
Recombinant Human MCAM/CD146 Protein (RP00101)
- Описание
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Overview
Product name Recombinant Human MCAM/CD146 Protein Catalog No. RP00101 Description Recombinant Human MCAM/CD146 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val24-Gly559) of human CD146/MCAM (Accession #NP_006491.2) fused with a 6×His tag at the C-terminus. Purity > 97% by SDS-PAGE. Endotoxin < 0.1 EU/μg of the protein by LAL method. Formulation Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation. Species Human Background
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.Product information
Synonym CD146; MUC18 Expression Host HEK293 cells Tag C-His Swiss-Prot Gene ID Usage guide
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. * For research use only. Not for therapeutic or diagnostic purposes.
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