быстрая доставка ~4 недели
Размер
- 10 μg
- 100 μg
- 50 μg
Recombinant Human CD38 Protein (RP02225)
- Описание
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Overview
Product name Recombinant Human CD38 Protein Catalog No. RP02225 Description Recombinant Human CD38 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (CD38(Val43-Ile300)&hFc(Glu99-Ala330)) of human CD38 (Accession #) fused with a Fc and His Tag at the C-terminal. . Bio-Activity ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human CD38, hFc-His tagged protein can bind Anti-CD38 Neutralizing antibody in a linear range of 0.98-64.14 ng/mL. Purity > 95% by SDS-PAGE. Formulation Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 11 % trehalose is added as protectants before lyophilization. Species Human Background
CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.Product information
Synonym CD38; T10; cADPr hydrolase 1 Expression Host HEK293 cells Tag C-hFc&His Swiss-Prot Gene ID Usage guide
Storage Store the lyophilized protein at -20°C to -80°C for long term.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.Reconstitution Reconstitute with deionized water * For research use only. Not for therapeutic or diagnostic purposes.
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