быстрая доставка ~4 недели
Размер
- 100 μg
- 1000 μg
- 500 μg
Recombinant Human CD3E&CD3G Heterodimer Protein (RP02025)
- Описание
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Overview
Product name Recombinant Human CD3E&CD3G Heterodimer Protein Catalog No. RP02025 Description Recombinant Human CD3 epsilon & CD3 delta Heterodimer Protein is produced by mammalian expression system. The target protein is expressed with sequence (Asp23-Asp126 (CD3E) & Gln23-Ser116 (CD3G)) of human CD3 epsilon & CD3 gamma Heterodimer (Accession #P07766 & P09693) fused with an Fc tag at the C-terminus. Bio-Activity Immobilized Human CD3 epsilon & CD3 gamma Heterodimer Protein at 0.5 μg/mL (100 μL/well), dose response curve for Anti-hCD3e mAb with the EC50 of 1.22 μg/mL determined by ELISA. Purity > 95% by SDS-PAGE. Endotoxin < 0.1 EU/μg of the protein by LAL method. Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation. Species Human Background
T-cell surface glycoprotein CD3 epsilon & CD3 gamma chain, also known as CD3E & CD3G , are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.Product information
Synonym IMD18; T3E; TCRE; CD3-GAMMA; IMD17; T3G Expression Host HEK293 cells Tag C-hFc Swiss-Prot Gene ID Usage guide
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. * For research use only. Not for therapeutic or diagnostic purposes.
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