быстрая доставка ~4 недели
Размер
- 100 μg
- 1000 μg
- 500 μg
Recombinant Human TNFSF5/CD40 Ligand Trimer Protein (RP02053)
- Описание
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Overview
Product name Recombinant Human TNFSF5/CD40 Ligand Trimer Protein Catalog No. RP02053 Description Recombinant Human TNFSF5/CD40 Ligand Trimer Protein is produced by mammalian expression system. The target protein is expressed with sequence (M113-L261 Trimer) of human CD40L/CD154 (Accession #P29965) fused with an Fc tag at the N-terminus. Bio-Activity Immobilized Biotinylated Human CD40 at 1 μg/mL (100 μL/well) on streptavidin precoated (0.2 μg/well) plate, dose response curve for Human CD40L with the EC50 of 15ng/mL determined by ELISA. Purity > 95% by SDS-PAGE. Endotoxin < 0.1 EU/μg of the protein by LAL method. Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation. Species Human Background
CD40 ligand or CD40L, also called CD154, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells.Product information
Synonym CD154; CD40L; HIGM1; IGM; IMD3; T-BAM; TNFSF5; TRAP; gp39; hCD40L Expression Host HEK293 cells Tag N-monomeric hFc Swiss-Prot Gene ID Usage guide
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. * For research use only. Not for therapeutic or diagnostic purposes.
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