быстрая доставка ~4 недели
Размер
- 100 μg
- 20 μg
- 200 μg
- 50 μg
Active Recombinant Human Trk-C/NTRK3 Protein (RP00288)
- Описание
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Overview
Product name Active Recombinant Human Trk-C/NTRK3 Protein Catalog No. RP00288 Description Active Recombinant Human Trk-C/NTRK3 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Cys32-Asp428) of human TrkC/NTRK3 (Accession #NP_001012338.1) fused with an Fc, 6×His tag at the C-terminus. Bio-Activity Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human NTF3 at 2 μg/mL (100 μL/well) can bind Recombinant human TrkC with a linear range of 22-90 ng/mL. Purity > 97% by SDS-PAGE. Endotoxin < 1.0 EU/μg of the protein by LAL method. Formulation Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation. Species Human Background
NT-3 growth factor receptor also known as neurotrophic tyrosine kinase receptor type 3 or TrkC tyrosine kinase or Trk-C receptor, is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in TrkC encoding gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.Product information
Synonym gp145(trkC); GP145-TrkC; TRKC Expression Host HEK293 cells Tag C-hFc&His Swiss-Prot Gene ID Usage guide
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. * For research use only. Not for therapeutic or diagnostic purposes.
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