быстрая доставка ~4 недели
Размер
- 10 μg
- 100 μg
- 50 μg
Recombinant Human B7-2/CD86 Protein (RP02220)
- Описание
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Overview
Product name Recombinant Human B7-2/CD86 Protein Catalog No. RP02220 Description Recombinant Human B7-2/CD86 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (B7-2(Leu26-Pro247)&hFc(Glu99-Ala330)) of human CD86 (Accession #) fused with a Fc Tag at the C-terminal. . Bio-Activity ELISA plate pre-coated by 2 μg/ml (100 μL/well) Human B7-2, hFc tagged protein can bind Human CTLA4, mFc-His tagged protein in a linear range of 0.048-2.694 ng/mL. Purity > 95% by SDS-PAGE. Formulation Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 82 % trehalose is added as protectants before lyophilization. Species Human Background
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.Product information
Synonym CD86; B7-2; B70; CD28LG2; LAB72; MGC34413 Expression Host HEK293 cells Tag C-hFc Swiss-Prot Gene ID Usage guide
Storage Store the lyophilized protein at -20°C to -80°C for long term.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.Reconstitution Reconstitute with deionized water * For research use only. Not for therapeutic or diagnostic purposes.
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