быстрая доставка ~4 недели
Размер
- 10 μg
- 100 μg
- 50 μg
Recombinant Human TNFSF9/4-1BB Ligand Protein (RP02246)
- Описание
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Overview
Product name Recombinant Human TNFSF9/4-1BB Ligand Protein Catalog No. RP02246 Description Recombinant Human TNFSF9/4-1BB Ligand Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (mFc(Pro99-Lys330)&4-1BB Ligand(Pro52-Glu254)) of human TNFSF9 (Accession #) fused with a Fc and His Tag at the N-terminal. . Purity > 95% by SDS-PAGE. Formulation Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 19 % trehalose is added as protectants before lyophilization. Species Human Background
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.Product information
Synonym 4-1BB Ligand; TNFSF9; CD137L Expression Host HEK293 cells Tag N-mFc&C-His Swiss-Prot Gene ID Usage guide
Storage Store the lyophilized protein at -20°C to -80°C for long term.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.Reconstitution Reconstitute with deionized water * For research use only. Not for therapeutic or diagnostic purposes.
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