быстрая доставка ~4 недели
Размер
- 10 μg
- 100 μg
- 50 μg
Recombinant Human PD-1/PDCD1/CD279 Protein (RP02237)
- Описание
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Overview
Product name Recombinant Human PD-1/PDCD1/CD279 Protein Catalog No. RP02237 Description Recombinant Human PD-1/PDCD1/CD279 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (PD-1(Phe24-Val170)&mFc(Pro99-Lys330)) of human PDCD1 (Accession #) fused with a Fc and His Tag at the C-terminal. . Bio-Activity ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human PD1, mFc-His tagged protein can bind Anti-PD-1 Neutralizing antibody in a linear range of 0.24-6.49 ng/mL. Purity > 95% by SDS-PAGE. Formulation Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 32 % trehalose is added as protectants before lyophilization. Species Human Background
This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.Product information
Synonym PDCD1; PD1; CD279; SLEB2 Expression Host HEK293 cells Tag C-mFc&His Swiss-Prot Gene ID Usage guide
Storage Store the lyophilized protein at -20°C to -80°C for long term.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.Reconstitution Reconstitute with deionized water * For research use only. Not for therapeutic or diagnostic purposes.
Product Protocols