быстрая доставка ~4 недели
Размер
- 10 μg
- 100 μg
- 20 μg
- 5 μg
- 50 μg
Recombinant Human LAIR-2/CD306 Protein (RP01034)
- Описание
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Overview
Product name Recombinant Human LAIR-2/CD306 Protein Catalog No. RP01034 Description Recombinant Human LAIR-2/CD306 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln22-Pro152) of human LAIR2 (Accession #NP_002279) fused with a 6×His tag at the C-terminus. Bio-Activity Measured by the ability of the immobilized protein to support the adhesion of HT-29 human colon adenocarcinoma cells. When 5 x 104?cells/well are added to rhLAIR-2 coated plates (50 μg/mL with 100 μL/well), approximately 50%-60% will adhere after 10 minutes at 37℃. Purity > 90% by SDS-PAGE. Endotoxin < 0.1 EU/μg of the protein by LAL method. Formulation Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation. Species Human Background
Leukocyte-associated immunoglobulin-like receptor 2 ( LAIR2 ), also known as CD36, is a 131 amino acid protein containing one lg-like C2-type domain, making it a member of the Ig superfamily. When compared to LAIR-1, its transmembrane counterpart, it shares 83% aa identity across the signal sequence and extracellular domains, the two LAIR proteins are thought to have arisen from a common gene ancestor and appear to share similar adhesion profiles. LAIR2 is thought to be secreted and may help modulate mucosal tolerance. As a natural competitor for LAIR1, soluble LAIR2 prevents binding of human LAIR1 to collagens and LAIR1 cross-linking, thereby regulating its inhibitory potential. LAIR2 is thought to be secreted and may help modulate mucosal tolerance.Product information
Synonym CD306; LAIR2; MGC71634 Expression Host HEK293 cells Tag C-His Swiss-Prot Gene ID Usage guide
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. * For research use only. Not for therapeutic or diagnostic purposes.
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