быстрая доставка ~4 недели
Размер
- 10 μg
- 1000 μg
- 50 μg
- 500 μg
Recombinant Human IL12RB1/CD212 Protein (RP00675)
- Описание
-
Overview
Product name Recombinant Human IL12RB1/CD212 Protein Catalog No. RP00675 Description Recombinant Human IL-12RB1/IL-12 R beta 1/IL-12RB Protein is produced by Human cells expression system. The target protein is expressed with sequence (Cys24-Glu540) of human IL-12RB1/IL-12 R beta 1/IL-12RB (Accession #P42701) fused with an Fc tag at the C-terminus. Purity > 95% by SDS-PAGE. Endotoxin < 1 EU/μg of the protein by LAL method. Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.Contact us for customized product form or formulation. Species Human Background
Interleukin12 receptor subunit beta 1 (IL12RB1) is a type I transmembrane protein that belongs to thehemopoietin receptor superfamily. IL12RB1 can spontaneously form homodimers and -oligomers, which areable to bind IL12 with only low affinity. IL12 high affinity receptor complex is composed of two subunitsdesignated IL12RB1 and IL12RB2. While IL12RB1 interacts with the IL-12p40 subunit, IL-12p35 is mainlyconnecting with IL12RB2. This receptor chain is also responsible for transmitting the IL12 signal into the cell.IL12RB1, to the contrary, is also part of the IL23R, where it interacts with the p40 subunit of IL23. IL12RB1 isexpressed in activated T cells, NK cells and B cells.Product information
Synonym CD212; IL12RB1; CD212; CD212 antigen; IL-12 receptor beta component; IL-12 receptor subunitbeta-1; IL12R; IL-12R subunit beta-1; IL12RB; IL-12RB1; IL-12R-BETA1; IL-12R-beta-1; interleukin-12 receptor beta-1 chain; interleukin-12 receptor subunit beta-1 Expression Host HEK293 cells Tag C-Fc Swiss-Prot Gene ID Usage guide
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in 1X PBS. * For research use only. Not for therapeutic or diagnostic purposes.
Product Protocols